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Now that we know why the body needs protein and where the idea of the anabolic window comes from, the question is: is there actually an anabolic windowand, if so, how do we get to a place that makes it possible to do so?There is at least another explanation, and it's one which has been around some time as far back as the 1600s. This explanation, known as "the muscle wall hypothesis," states that there is one "densely packed, muscular outer layer" which separates the skeletal muscle, or muscle tissue, from the extracellular fluid, or fluid surrounding and supporting the muscle. This dense layer of protein is known as the muscle wall, and is so dense that it impedes the diffusion of nutrients out of the muscle tissue and into the bloodstream and the cells of the body. The fact that the outer layer is so dense and so thick makes it difficult to reach into and the result is an accumulation of protein within the muscle tissue, and in cells that use up those nutrients. It is this accumulation that leads to anabolic response, or an increased amount of protein available for the use or uptake by the cell.Here is a quote from the website of the Academy of Nutrition and Dietetics:In addition to the protein that exists within the muscle cells, approximately 85 percent of the muscle protein present within the body is derived from the liver, kidneys and other tissues. The liver contains approximately 50-65 percent of the dietary protein of the body with the majority of it supplied by the amino acid lysine, which is primarily derived from proteins of animal origin. The remaining 25-30 percent is provided by the various fats, carbohydrates, vitamins, minerals and fatty acids (carbohydrates) in the diet.When the amount of amino acids within the muscle tissue is considered, it becomes clear that almost 1/3 of the amino acids must come from the liver to account for 95-100% of the amino acids and in turn, the amino acids in the muscle tissue are necessary for the creation of new protein. The problem arises when the body does not have enough of the liver to meet its needs and so the protein is accumulated and the body can not utilize it.If the concentration of amino acids in the muscle tissues is insufficient for their purposes, there are multiple other processes by which the body cannot use them. Protein breakdown occurs in numerous reactions in the body. First, protein cannot be fully utilized without an energy source. The most recent research, which included studying rats fed diets made up of 70% protein, found that the animals with the lowest levels of protein in their tissues also had the lowestSimilar articles: